E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

Diabetologia ·Vol. 46 ·No. 1 ·2003-01-00 ·Pages 136-7

Love-Gregory L, Wasson J, Lin J, Skolnick G, Suarez B, Permutt MA

Abstract

暂无摘要

MeSH Terms

Adenosine Triphosphate/physiology Diabetes Mellitus, Type 2/genetics Genetic Predisposition to Disease Genetic Variation Humans Islets of Langerhans/metabolism Polymorphism, Single Nucleotide Potassium Channels, Inwardly Rectifying/genetics,metabolism Receptors, Cytoplasmic and Nuclear/genetics Transcription Factors/genetics Whites/genetics

Chemicals

Potassium Channels, Inwardly Rectifying Receptors, Cytoplasmic and Nuclear Transcription Factors Adenosine Triphosphate

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Love-Gregory L

Wasson J

Lin J

Skolnick G

Suarez B

Permutt M A

Article Info

Journal

Diabetologia

Abbr.

Diabetologia

ISSN

0012-186X

DOI

10.1007/s00125-002-0947-x

Published

2003-01-00

Pages

136-7

Language

English

Region

Germany

NLM ID

0006777

Subset

External Links

PubMed source DOI: 10.1007/s00125-002-0947-x View journal details

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E23K single nucleotide polymorphism in the islet ATP-sensitive potassium channel gene (Kir6.2) contributes as much to the risk of Type II diabetes in Caucasians as the PPARgamma Pro12Ala variant.

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