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PMID: 1269909 Published · ppublish English Journal Article

The effects of hitchhiking on a gene for recombination.

Genetics ·Vol. 82 ·No. 3 ·1976-03-25 ·Pages 547-58

Strobeck C, Smith JM, Charlesworth B

Abstract

This paper proposes that alleles increasing recombination rates may be selected for as a result of the perturbing effects of the spread of selectively favored alleles on neighboring loci maintained polymorphic by sleection. The recombination genes are favored since their presence increases the production of selectively advantageous types of gametes with which they tend to remain associated. Numerical examples are presented, and some consequences of this model discussed. One such consequence is the wicespread existence of polymorphism for genes affecting recombination values.

MeSH Terms
Alleles Gene Frequency Models, Biological Polymorphism, Genetic Recombination, Genetic Selection, Genetic
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Strobeck C
Smith J M
Charlesworth B
References (5)
5 references, click to expand
  1. Selection for reduced crossing over in Drosophila melanogaster.
    Genetics. 1974 Mar;76(3):447-51 PMID: 4208855
  2. Application of method of small parameters to multi-niche population genetic models.
    Theor Popul Biol. 1972 Jun;3(2):186-209 PMID: 4667083
  3. Modification of recombination frequency in Drosophila. II. The polygenic control of crossing over.
    Genetics. 1971 Sep;69(1):85-96 PMID: 5002415
  4. The effect of genetic linkage on the mean fitness of a population.
    Proc Natl Acad Sci U S A. 1971 May;68(5):984-6 PMID: 5280533
  5. Selection for high mutation rates in chemostats.
    Genetics. 1974 Jun;77(2):169-84 PMID: 4603159
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
Published
1976-03-25
Pages
547-58
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1213474
Subset
IM
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