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PMID: 1270155 Published · ppublish English Journal Article

Strain-dependent differences in murine susceptibility to toxoplasma.

Infection and immunity ·Vol. 13 ·No. 5 ·1976-05-00 ·Pages 1528-30

Araujo FG, Williams DM, Grumet FC, Remington JS

Abstract

Susceptibility of seven inbred and outbred strains of mice to infection with trophozoites of Toxoplasma gondii at two different doses was determined. Stroking strain differences in susceptibility and changes of susceptibility with dosage change were seen. The data are consistent with the hypothesis that this may be due to genetic factors.

MeSH Terms
Animals Female Male Mice Mice, Inbred BALB C Mice, Inbred C3H Mice, Inbred C57BL Mice, Inbred DBA Species Specificity Toxoplasma/pathogenicity Toxoplasmosis/microbiology,mortality
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Araujo F G
Williams D M
Grumet F C
Remington J S
References (6)
6 references, click to expand
  1. Histocompatibility-linked genetic control of disease susceptibility. Murine lymphocytic choriomeningitis virus infection.
    J Exp Med. 1973 May 1;137(5):1201-12 PMID: 4702099
  2. The use of killed vaccines in immunization against an intracellular parasite: Toxoplasma gondii.
    J Immunol. 1972 Feb;108(2):425-31 PMID: 5049090
  3. Autoimmune murine thyroiditis relation to histocompatibility (H-2) type.
    Science. 1971 Dec 10;174(4014):1137-9 PMID: 5133731
  4. The effect of histocompatibility-2 type on response to friend leukemia virus in mice.
    J Exp Med. 1968 Mar 1;127(3):465-73 PMID: 5636554
  5. Ocular toxoplasmosis; pathogenesis, diagnosis and treatment.
    AMA Arch Ophthalmol. 1958 Feb;59(2):260-79 PMID: 13497381
  6. Studies on chronic toxoplasmosis; the relation of infective dose to residual infection and to the possibility of congenital transmission.
    Am J Ophthalmol. 1958 Nov;46(5 Pt 2):261-7; discussion 268 PMID: 13595073
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1976-05-00
Pages
1528-30
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC420794
Subset
IM
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