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PMID: 1273829 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Genetic independence between the HL--A system and deficits in the first and sixth components of complement.

Tissue antigens ·Vol. 7 ·No. 2 ·1976-02-00 ·Pages 97-104

Mittal KK, Wolski KP, Lim D, Gewurz A, Gewurz H, Schmid FR

Abstract

From two families, one with Clr deficiency and the other with C6 deficiency, evidence was obtained suggesting genetic independence between the transmission of a 50% deficit in the functional activity of these two complement components and the inheritance of the HL--A system, the ABO system, and the sex of individuals.

MeSH Terms
ABO Blood-Group System Adult Aged Child Child, Preschool Complement C1/deficiency Complement C6/deficiency Complement System Proteins/deficiency Female Genotype HLA Antigens Histocompatibility Antigens Histocompatibility Testing Humans Infant Male Middle Aged Pedigree Sex Factors
Chemicals
ABO Blood-Group System Complement C1 Complement C6 HLA Antigens Histocompatibility Antigens Complement System Proteins
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Mittal K K
Wolski K P
Lim D
Gewurz A
Gewurz H
Schmid F R
Article Info
Journal
Tissue antigens
Abbr.
Tissue Antigens
ISSN
0001-2815
DOI
10.1111/j.1399-0039.1976.tb01038.x
Published
1976-02-00
Pages
97-104
Language
English
Region
England
NLM ID
0331072
Subset
IM
External Links
PubMed source DOI: 10.1111/j.1399-0039.1976.tb01038.x View journal details
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