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PMID: 1276381 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

A possible mechanism for concentrating sodium and potassium in the cell nucleus.

Biophysical journal ·Vol. 16 ·No. 5 ·1976-05-00 ·Pages 527-33

Moore RD, Morrill GA

Abstract

A dynamic, nonequilibrium mechanism is proposed for concentrating both Na+ and K+ in the cell nucleus. The model is consistent with experiment observations and with known properties of cell membranes. This model could explaing the high nucleoplasm to cytoplasm ratios of Na+ and/or K+ reported for liver kidney, thymus, frog skin, ascites cells, and amphibian oocytes.

MeSH Terms
Animals Ascitic Fluid/metabolism Biological Transport, Active Cell Membrane/metabolism Cell Nucleus/metabolism Cytoplasm/metabolism Energy Transfer Female Kidney/metabolism Liver/metabolism Methods Models, Biological Oocytes/metabolism Organ Specificity Potassium/metabolism Skin/metabolism Sodium/metabolism Thymus Gland/metabolism
Chemicals
Sodium Potassium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Moore R D
Morrill G A
References (21)
21 references, click to expand
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Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
DOI
10.1016/S0006-3495(76)85707-4
Published
1976-05-00
Pages
527-33
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1334873
Subset
IM
External Links
PubMed source DOI: 10.1016/S0006-3495(76)85707-4 PMC Full Text View journal details
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