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PMID: 12824334 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Integrated databanks access and sequence/structure analysis services at the PBIL.

Nucleic acids research ·Vol. 31 ·No. 13 ·2003-07-01 ·Pages 3393-9

Perrière G, Combet C, Penel S, Blanchet C, Thioulouse J, Geourjon C, Grassot J, Charavay C, Gouy M, Duret L, Deléage G

Abstract

The World Wide Web server of the PBIL (Pôle Bioinformatique Lyonnais) provides on-line access to sequence databanks and to many tools of nucleic acid and protein sequence analyses. This server allows to query nucleotide sequence banks in the EMBL and GenBank formats and protein sequence banks in the SWISS-PROT and PIR formats. The query engine on which our data bank access is based is the ACNUC system. It allows the possibility to build complex queries to access functional zones of biological interest and to retrieve large sequence sets. Of special interest are the unique features provided by this system to query the data banks of gene families developed at the PBIL. The server also provides access to a wide range of sequence analysis methods: similarity search programs, multiple alignments, protein structure prediction and multivariate statistics. An originality of this server is the integration of these two aspects: sequence retrieval and sequence analysis. Indeed, thanks to the introduction of re-usable lists, it is possible to perform treatments on large sets of data. The PBIL server can be reached at: http://pbil.univ-lyon1.fr.

MeSH Terms
Databases, Genetic Internet Models, Molecular Nucleic Acids/chemistry Protein Conformation Protein Structure, Secondary Proteins/chemistry Sequence Alignment Sequence Analysis, DNA Sequence Analysis, Protein Sequence Analysis, RNA Sequence Homology Software Systems Integration User-Computer Interface
Chemicals
Nucleic Acids Proteins
Authors & Affiliations
11 authors, click to expand affiliations / ORCID
Perrière Guy
Laboratoire de Biométrie et Biologie Evolutive, UMR CNRS no. 5558, Université Claude Bernard, Lyon 1, 43 bd du 11 Novembre 1918, 69622 Villeurbanne Cedex, France. [email protected]
Combet Christophe
Penel Simon
Blanchet Christophe
Thioulouse Jean
Geourjon Christophe
Grassot Julien
Charavay Céline
Gouy Manolo
Duret Laurent
Deléage Gilbert
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkg530
Email
[email protected]
Published
2003-07-01
Pages
3393-9
Language
English
Region
England
NLM ID
0411011
PMCID
PMC168937
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/gkg530 PMC Full Text View journal details
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