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PMID: 12825827 Published · ppublish English Journal Article Review

The role of catechol-O-methyltransferase in the inactivation of catecholestrogen.

Cellular and molecular neurobiology ·Vol. 23 ·No. 3 ·2003-06-00 ·Pages 289-91

Creveling CR

Abstract

暂无摘要

MeSH Terms
Animals Brain/enzymology Brain Chemistry/physiology Breast Neoplasms/enzymology,genetics,physiopathology Catechol O-Methyltransferase/metabolism DNA Damage/genetics Estrogens, Catechol/metabolism Humans Mutation/genetics
Chemicals
Estrogens, Catechol Catechol O-Methyltransferase
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Creveling C R
[email protected]
References (9)
9 references, click to expand
  1. Estrogens as endogenous genotoxic agents--DNA adducts and mutations.
    J Natl Cancer Inst Monogr. 2000;(27):75-93 PMID: 10963621
  2. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT inhibitors.
    Pharmacol Rev. 1999 Dec;51(4):593-628 PMID: 10581325
  3. An association between the allele coding for a low activity variant of catechol-O-methyltransferase and the risk for breast cancer.
    Cancer Res. 1997 Dec 15;57(24):5493-7 PMID: 9407957
  4. Catecholoestrogens (2-and 4-hydroxyoestrogens): chemistry, biogenesis, metabolism, occurrence and physiological significance.
    Acta Endocrinol Suppl (Copenh). 1980;232:1-127 PMID: 6770572
  5. Genetic polymorphisms in catechol-O-methyltransferase, menopausal status, and breast cancer risk.
    Cancer Res. 1998 May 15;58(10):2107-10 PMID: 9605753
  6. Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1----q11.2.
    Genomics. 1992 Apr;12(4):822-5 PMID: 1572656
  7. Enzymatic O-methylation of epinephrine and other catechols.
    J Biol Chem. 1958 Sep;233(3):702-5 PMID: 13575440
  8. Inheritance of low erythrocyte catechol-o-methyltransferase activity in man.
    Am J Hum Genet. 1977 Mar;29(2):125-35 PMID: 848488
  9. Estrogen metabolism by conjugation.
    J Natl Cancer Inst Monogr. 2000;(27):113-24 PMID: 10963623
Article Info
Journal
Cellular and molecular neurobiology
Abbr.
Cell Mol Neurobiol
ISSN
0272-4340
DOI
10.1023/a:1023680302975
Email
[email protected]
Published
2003-06-00
Pages
289-91
Language
English
Region
United States
NLM ID
8200709
Subset
IM
External Links
PubMed source DOI: 10.1023/a:1023680302975 View journal details
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