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PMID: 12837239 Published · ppublish English Journal Article Review

"Recruitment signals" from apoptotic cells: invitation to a quiet meal.

Cell ·Vol. 113 ·No. 7 ·2003-06-27 ·Pages 817-20

Ravichandran KS

Abstract

An evolutionarily conserved machinery exists for engulfment of apoptotic cells from worm to mammals. New observations suggest that corpse clearance is tightly linked to apoptosis and that dying cells use both recruitment and eat-me signals for phagocyte attraction and recognition.

MeSH Terms
Animals Apoptosis/genetics Eukaryotic Cells/metabolism Humans Immune Tolerance/genetics Phagocytes/cytology,metabolism Phagocytosis/genetics Phospholipids/genetics,metabolism Receptors, Cell Surface/genetics,metabolism Signal Transduction/genetics
Chemicals
Phospholipids Receptors, Cell Surface
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Ravichandran Kodi S
Carter Immunology Center and the Department of Microbiology, University of Virginia, Charlottesville, VA 22908, USA. [email protected]
Article Info
Journal
Cell
Abbr.
Cell
ISSN
0092-8674
DOI
10.1016/s0092-8674(03)00471-9
Email
[email protected]
Published
2003-06-27
Pages
817-20
Language
English
Region
United States
NLM ID
0413066
Subset
IM
External Links
PubMed source DOI: 10.1016/s0092-8674(03)00471-9 View journal details
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