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PMID: 12855382 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Pattern recognition molecules and innate immunity to parasites.

Trends in parasitology ·Vol. 19 ·No. 7 ·2003-07-00 ·Pages 312-9

McGuinness DH, Dehal PK, Pleass RJ

Abstract

Recent pioneering advances in understanding how plants, insects and worms eliminate pathogens has led to the realization that innate immunity plays a vital role in protecting humans from infection. This comprehensive review examines the molecules involved in innate immune responses, how they act to control parasites and if their engagement can explain many immune features characteristic of parasitic infections.

MeSH Terms
Animals Host-Parasite Interactions Humans Immunity, Innate Membrane Glycoproteins/physiology Parasites/immunology Parasitic Diseases/immunology,parasitology Phagocytes/physiology Receptors, Cell Surface/physiology Toll-Like Receptors
Chemicals
Membrane Glycoproteins Receptors, Cell Surface Toll-Like Receptors
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
McGuinness David H
Department of Molecular & Cellular Pathology, University of Dundee Medical School, Ninewells Hospital, DD1 9SY, Dundee, UK.
Dehal Prabhjyot K
Pleass Richard J
Article Info
Journal
Trends in parasitology
Abbr.
Trends Parasitol
ISSN
1471-4922
Published
2003-07-00
Pages
312-9
Language
English
Region
England
NLM ID
100966034
Subset
IM
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