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PMID: 12948667 Published · ppublish English News

The genetics of gene expression and gene mapping.

Trends in biotechnology ·Vol. 21 ·No. 9 ·2003-09-00 ·Pages 377-8

Kraft P, Horvath S

Abstract

A recent publication has shown that a significant portion of gene expression levels are under genetic control in different organisms, that there are hotspot regions in the genome that control the expression of many other genes, and how gene expression data can be used to localize genes that affect clinical traits.

MeSH Terms
Adipose Tissue/metabolism Animals Chromosome Mapping Gene Expression Regulation/genetics Genetic Heterogeneity Genetic Predisposition to Disease/genetics Humans Mice Models, Genetic Quantitative Trait Loci/genetics Regulatory Sequences, Nucleic Acid/genetics
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kraft Peter
Department of Biostatistics, UCLA School of Public Health, Box 951772 51-236C CHS, Los Angeles, CA 90095-1772, USA.
Horvath Steve
Article Info
Journal
Trends in biotechnology
Abbr.
Trends Biotechnol
ISSN
0167-7799
DOI
10.1016/S0167-7799(03)00191-4
Published
2003-09-00
Pages
377-8
Language
English
Region
England
NLM ID
8310903
Subset
IM
External Links
PubMed source DOI: 10.1016/S0167-7799(03)00191-4 View journal details
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