QSAR Study on tadpole narcosis.

This paper deals with a Quantitative Structure-Activity Relationship (QSAR) study on a large set of 123 compounds using a combination of topological indices as well as Abraham's molecular descriptors. The results have shown that an excellent model (R=0.9542) is obtained in hexa-parametric correlation containing W, logRB (topological indices) along with R2, sigmapi2H, sigmabeta2O and Vx as the correlating parameters. The results are discussed critically.