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PMID: 13329850 Published · ppublish English Journal Article

The Treponema pallidum immobilization test.

Bulletin of the World Health Organization ·Vol. 14 ·No. 2 ·1956-00-00 ·Pages 263-88

NIELSEN HA, REYN A

Abstract

The authors first discuss the principle of the Treponema pallidum immobilization (TPI) test, considered both as a qualitative and as a quantitative test, and then various specific aspects of passage of the Nichols strain of treponeme in rabbit testes. A number of important technical details and modifications in the test procedure are then reviewed, and the clinical value of the test is discussed.The sensitivity of the TPI test is considerably greater than that of the serological tests for syphilis more usually performed, and its specificity is also remarkably high. However, it is stressed that, at the present stage of development, the greatest value of the TPI test lies in its use as an excellent aid to diagnosis rather than as a test of cure.

Keywords
SYPHILIS/diagnosis
MeSH Terms
Animals Humans Rabbits Syphilis/diagnosis Treponema Immobilization Test Treponema pallidum
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
NIELSEN H A
REYN A
References (62)
62 references, click to expand
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Article Info
Journal
Bulletin of the World Health Organization
Abbr.
Bull World Health Organ
ISSN
0042-9686
Published
1956-00-00
Pages
263-88
Language
English
Region
Switzerland
NLM ID
7507052
PMCID
PMC2538021
Subset
OM
External Links
PubMed source PMC Full Text View journal details
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