Studies with the serotonin precursor, 5-hydroxytryptophan, in experimental animals and man.

The Journal of clinical investigation ·Vol. 36 ·No. 11 ·1957-11-00 ·Pages 1594-9

DAVIDSON J, SJOERDSMA A, LOOMIS LN, UDENFRIEND S

Abstract

暂无摘要

Keywords

SEROTONIN/metabolism TRYPTOPHAN/related compounds

MeSH Terms

5-Hydroxytryptophan Humans Male Serotonin/metabolism Tryptophan/analogs & derivatives

Chemicals

Serotonin Tryptophan 5-Hydroxytryptophan

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

DAVIDSON J

SJOERDSMA A

LOOMIS L N

UDENFRIEND S

References (12)

12 references, click to expand

Malignant carcinoid of the small intestine with metastases to the liver, valvular disease of the right side of the heart (pulmonary stenosis and tricuspid regurgitation without septal defects), peripheral vasomotor symptoms, bronchoconstriction, and an unusual type of cyanosis; a clinical and pathologic syndrome.
Am Heart J. 1954 Jun;47(5):795-817 PMID: 13158264
A clinical, physiologic and biochemical study of patients with malignant carcinoid (argentaffinoma).
Am J Med. 1956 Apr;20(4):520-32 PMID: 13302231
Production of renal cortical necrosis with serotonin (5-hydroxytryptamine); theoretical relationship to abruptio placentae.
Obstet Gynecol. 1955 Jun;5(6):781-8 PMID: 14384126
Pharmacology of indole-alkylamines.
Pharmacol Rev. 1954 Dec;6(4):425-87 PMID: 13236482
The reproducibility and constancy of the platelet count.
Am J Clin Pathol. 1953 Jan;23(1):15-26 PMID: 13016502
Studies on the functional circulatory influence from metastasizing carcinoid (argentaffine, enterochromaffine) tumours and their possible relation to enteramine production. I. The chemistry of carcinoid tumours.
Acta Med Scand. 1955 Nov 10;152(4):311-31 PMID: 13292154
[Kidney damage with cortical necrosis in rats under treatment with 5-oxytryptamin; additional experimental contribution to the question of endocrine activity of carcinoids].
Schweiz Med Wochenschr. 1955 May 28;85(22):541-4 PMID: 14396315
Evidence that serotonin has a role in brain function.
Science. 1955 Nov 18;122(3177):968 PMID: 13274056
[Pronounced thrombocytosis in rats under treatment with 5-oxytryptamin; experimental contribution to the question of endocrine activity of carcinoids].
Schweiz Med Wochenschr. 1955 Apr 16;85(16):368-70 PMID: 14385752
The identification of 5-hydroxy-3-indoleacetic acid in normal urine and a method for its assay.
J Biol Chem. 1955 Oct;216(2):499-505 PMID: 13271330
The estimation of 5-hydroxytryptamine (serotonin) in biological tissues.
J Biol Chem. 1955 Jul;215(1):337-44 PMID: 14392167
Increase in tissue serotonin following administration of its precursor 5-hydroxytryptophan.
J Biol Chem. 1957 Feb;224(2):803-10 PMID: 13405909

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103558

Published

1957-11-00

Pages

1594-9

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC1072765

Subset

External Links

PubMed source DOI: 10.1172/JCI103558 PMC Full Text View journal details

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Studies with the serotonin precursor, 5-hydroxytryptophan, in experimental animals and man.

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