Fate of non-virulent group A streptococci phagocytized by human and mouse neutrophils.

The Journal of experimental medicine ·Vol. 106 ·No. 6 ·1957-12-01 ·Pages 777-86

WILSON AT, WILEY GG, BRUNO P

Abstract

The fate of non-virulent group A streptococci phagocytized in vitro has been investigated by destroying the phagocyte with electric current and observing whether the liberated cocci multiply. Human and mouse peripheral blood neutrophils quickly injure ingested cocci, the time required to produce 50 per cent non-survival of chains being 8 and 6(3/4) minutes, respectively.

Keywords

PHAGOCYTOSIS STREPTOCOCCUS

MeSH Terms

Animals Humans Mice Neutrophils Phagocytes Phagocytosis Streptococcus Streptococcus pyogenes

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

WILSON A T

WILEY G G

BRUNO P

References (8)

8 references, click to expand

STUDIES ON THE MECHANISM OF RECOVERY IN PNEUMONIA DUE TO FRIEDLADER'S BACILLUS : III. THE ROLE OF "SURFACE PHAGOCYTOSIS" IN THE DESTRUCTION OF THE MICROORGANISMS IN THE LUNG.
J Exp Med. 1947 Aug 31;86(3):257-66 PMID: 19871676
The survival of staphylococci within human leukocytes.
J Exp Med. 1952 Feb;95(2):209-30 PMID: 14907971
The egestion of phagocytized particles by leukocytes.
J Exp Med. 1953 Oct;98(4):305-10 PMID: 13096656
Diphosphopyridine nucleotidase as an extracellular product of streptococcal growth and its possible relationship to leukotoxicity.
J Exp Med. 1957 Jul 1;106(1):27-37 PMID: 13439112
Interaction between phagocytes and pathogenic microorganisms.
Bacteriol Rev. 1956 Jun;20(2):94-132 PMID: 13341822
THE SLOW RECOVERY OF BACTERIA FROM THE TOXIC EFFECTS OF PENICILLIN.
J Bacteriol. 1949 Oct;58(4):475-90 PMID: 16561809
Mouse protection and enhancement of phagocytosis by antisera to Streptococcus pyogenes.
Br J Exp Pathol. 1956 Aug;37(4):406-14 PMID: 13364151
The leukotoxic action of streptococci.
J Exp Med. 1957 May 1;105(5):463-84 PMID: 13428916

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.106.6.777

Published

1957-12-01

Pages

777-86

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2136833

Subset

External Links

PubMed source DOI: 10.1084/jem.106.6.777 PMC Full Text View journal details

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Fate of non-virulent group A streptococci phagocytized by human and mouse neutrophils.

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