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PMID: 13513747 Published · ppublish English Journal Article

Studies on the biochemical defect of pernicious anemia. I. In vitro observations on oxygen consumption, heme synthesis and deoxyribonucleic acid synthesis by pernicious anemia bone marrow.

The Journal of clinical investigation ·Vol. 37 ·No. 2 ·1958-02-00 ·Pages 166-71

THOMAS ED, LOCHTE HL

Abstract

暂无摘要

Keywords
ANEMIA PERNICIOUS/metabolism BONE MARROW/metabolism DESOXYRIBONUCLEIC ACID/metabolism FOLIC ACID/effects HEMOGLOBIN VITAMIN B12/effects
MeSH Terms
Anemia Anemia, Pernicious/metabolism Bone Marrow/metabolism DNA/metabolism DNA Replication Folic Acid/pharmacology Heme Hemoglobins Humans In Vitro Techniques Oxygen Consumption Vitamin B 12/pharmacology
Chemicals
Hemoglobins Heme DNA Folic Acid Vitamin B 12
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
THOMAS E D
LOCHTE H L
References (12)
12 references, click to expand
  1. The relationship of vitamin B12 and folic acid in megaloblastic anemias.
    J Lab Clin Med. 1954 Jul;44(1):118-32 PMID: 13174929
  2. The serum vitamin B12 concentration in pernicious anemia.
    J Lab Clin Med. 1954 Nov;44(5):715-22 PMID: 13212247
  3. Role of vitamin B12 in the metabolism of microorganisms.
    Vitam Horm. 1955;(13):101-36 PMID: 13291771
  4. Rôle of vitamin B12 in nucleic acid metabolism. IV. Metabolism of C14-labeled thymidine by Lactobacillus leichmannii.
    J Biol Chem. 1956 Jun;220(2):521-6 PMID: 13331910
  5. Water-soluble vitamins. I. Vitamin B12, folic acid, choline, and para-aminobenzoic acid.
    Annu Rev Biochem. 1956;25:397-434 PMID: 13363317
  6. Iron Metabolism. Heme Synthesis in Vitro by Immature Erythrocytes.
    Science. 1949 Oct 14;110(2859):396-8 PMID: 17844560
  7. Interrelationship of folic acid, vitamin B12 and ascorbic acid in patients with megaloblastic anemia.
    Am J Clin Nutr. 1955 Jan-Feb;3(1):30-44 PMID: 14349900
  8. In vitro studies of erythropoiesis. I. The effect of normal serum on heme synthesis and oxygen consumption by bone marrow.
    Blood. 1955 Jun;10(6):600-11 PMID: 14378279
  9. The effect of various metabolites on the growth of marrow cells in vitro.
    Blood. 1955 Jul;10(7):735-52 PMID: 14389386
  10. Culture of human bone marrow in vitro; the reversibility between normoblastic and megaloblastic series of cells.
    J Clin Pathol. 1952 Feb;5(1):67-84 PMID: 14917773
  11. Observations on the effects of vitamin B12, liver extracts, folic acid and thymine on the maturation of megaloblasts in culture.
    Blood. 1952 May;7(5):522-5 PMID: 14925145
  12. Desoxyribonucleic acid synthesis by bone marrow cells in vitro.
    Blood. 1957 Dec;12(12):1086-95 PMID: 13489038
Article Info
Journal
The Journal of clinical investigation
Abbr.
J Clin Invest
ISSN
0021-9738
DOI
10.1172/JCI103595
Published
1958-02-00
Pages
166-71
Language
English
Region
United States
NLM ID
7802877
PMCID
PMC293073
Subset
OM
External Links
PubMed source DOI: 10.1172/JCI103595 PMC Full Text View journal details
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