Studies on the biosynthesis of cholesterol. 5. Biosynthesis of squalene from DL-3-hydroxy-3-methyl [2-14C] pentano-5-lactone.

The Biochemical journal ·Vol. 69 ·No. 1 ·1958-05-00 ·Pages 146-55

CORNFORTH JW, CORNFORTH RH, POPJAK G, GORE IY

Abstract

暂无摘要

Keywords

CHOLESTEROL/metabolism PYRANS/metabolism SQUALENE/metabolism

MeSH Terms

Cholesterol/metabolism Lactones Lipid Metabolism Pyrans/metabolism Squalene/metabolism

Chemicals

Lactones Pyrans Squalene Cholesterol

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

CORNFORTH J W

CORNFORTH R H

POPJAK G

GORE I Y

References (11)

11 references, click to expand

Studies of cholesterol biosynthesis. II. Distribution of acetate carbon in the ring structure.
Biochem J. 1953 Jul;54(4):597-601 PMID: 13058957
Enzymatic carboxylation of beta-hydroxyisovaleryl coenzyme A.
J Biol Chem. 1956 Apr;219(2):539-50 PMID: 13319276
Biosynthesis of squalene and cholesterol in vitro from acetate-1-C14.
Arch Biochem Biophys. 1954 Jan;48(1):102-6 PMID: 13125576
Studies on the biosynthesis of cholesterol. 3. Distribution of 14C in squalene biosynthesized from [Me-14C]acetate.
Biochem J. 1954 Nov;58(3):403-7 PMID: 13208629
The origin of the issoctyl side chain of cholesterol.
J Biol Chem. 1952 Mar;195(1):439-46 PMID: 14938398
Discovery of a new acetate-replacing factor.
J Bacteriol. 1956 Oct;72(4):519-24 PMID: 13366957
Biological synthesis of cholesterol.
Harvey Lect. 1952-1953;48:68-88 PMID: 13142481
Enzymatic synthesis of branched chain acids from amino acids.
Fed Proc. 1955 Sep;14(3):762-4 PMID: 13262140
The significance of certain carboxylic acids as intermediates in the biosynthesis of cholesterol.
Biochim Biophys Acta. 1957 Mar;23(3):472-9 PMID: 13426156
The enzymatic cleavage of beta-hydroxy-beta-methylglutaryl coenzyme A to acetoacetate and acetyl coenzyme A.
J Biol Chem. 1955 Oct;216(2):727-36 PMID: 13271348
Appendix 2. Preparation of solid samples for assay of C.
Biochem J. 1950 May;46(5):560-1 PMID: 16748694

Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

Published

1958-05-00

Pages

146-55

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1196527

Subset

External Links

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