Studies on the relationship between glucose oxidation and intermediary metabolism. I. The influence of glycolysis on the synthesis of cholesterol and fatty acid in normal liver.

The Journal of clinical investigation ·Vol. 37 ·No. 8 ·1958-08-00 ·Pages 1185-95

SIPERSTEIN MD, FAGAN VM

Abstract

暂无摘要

Keywords

CHOLESTEROL/metabolism FATTY ACIDS/metabolism GLUCOSE/metabolism LIVER/metabolism

MeSH Terms

Cholesterol/metabolism Fatty Acids/metabolism Glucose/metabolism Glycolysis Lipid Metabolism Liver/metabolism Oxidation-Reduction

Chemicals

Fatty Acids Cholesterol Glucose

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

SIPERSTEIN M D

FAGAN V M

References (32)

32 references, click to expand

A revision of the Schoenheimer-Sperry method for cholesterol determination.
J Biol Chem. 1950 Nov;187(1):97-106 PMID: 14794694
Cofactor requirements for lipogenesis.
J Biol Chem. 1953 Nov;205(1):303-8 PMID: 13117909
Lipogenesis and glucose oxidation in the liver of the alloxan-diabetic rat.
J Biol Chem. 1950 Oct;186(2):527-34 PMID: 14794647
Lipogenesis in particle-free extracts of rat liver. I. Substrates and cofactor requirements.
J Biol Chem. 1957 May;226(1):407-16 PMID: 13428773
The fraction of glucose catabolized via the glycolytic pathway.
J Biol Chem. 1955 Feb;212(2):555-63 PMID: 14353856
On the conversion of squalene to lanosterol in vitro.
J Biol Chem. 1957 Jun;226(2):921-30 PMID: 13438881
A study of glucose oxidation in whole tissue homogenates.
J Biol Chem. 1953 Nov;205(1):409-22 PMID: 13117919
Role of glycolysis in fatty acid and cholesterol synthesis in normal and diabetic rats.
Science. 1957 Nov 15;126(3281):1012-3 PMID: 13486050
A method for isolating intact mitochondria and nuclei from the same homogenate, and the influence of mitochondrial destruction on the properties of cell nuclei.
J Biophys Biochem Cytol. 1955 Mar;1(2):139-53 PMID: 14381436
C14 studies in carbohydrate metabolism. I. The oxidation of glucose in normal human subjects.
J Biol Chem. 1954 Dec;211(2):575-92 PMID: 13221566
Studies on the relationship between glucose oxidation and intermediary metabolism. II. The role of glucose oxidation in lipogenesis in diabetic rat liver.
J Clin Invest. 1958 Aug;37(8):1196-1201 PMID: 13563649
Differential conversion of specifically labeled glucose to C14O2.
J Biol Chem. 1954 Dec;211(2):773-9 PMID: 13221582
Functional group of coenzyme A and its metabolic relations, especially in the fatty acid cycle.
Fed Proc. 1953 Sep;12(3):683-91 PMID: 13107740
Lipogenesis of the intact alloxan-diabetic rat.
J Biol Chem. 1954 Aug;209(2):635-40 PMID: 13192116
Cholesterol synthesis by liver. I. Influence of fasting and of diet.
J Biol Chem. 1952 May;196(2):569-73 PMID: 12981000
Studies on carbohydrate metabolism in rat liver slices. VII. Evaluation of the Embden-Meyerhof and phosphogluconate oxidation pathways.
J Biol Chem. 1956 Jun;220(2):619-26 PMID: 13331920
Previous nutritional state and glucose conversion to fatty acids in liver slices.
J Biol Chem. 1950 Aug;185(2):845-56 PMID: 14774432
The metabolism of variously labeled glucose in rat liver in vivo.
J Biol Chem. 1957 Feb;224(2):971-85 PMID: 13405926
An isotope tracer study of glucose catabolism pathways in liver.
J Biol Chem. 1956 Apr;219(2):691-704 PMID: 13319290
The quantitatively minor role of carbohydrate in oxidative metabolism by skeletal muscle in intact man in the basal state; measurements of oxygen and glucose uptake and carbon dioxide and lactate production in the forearm.
J Clin Invest. 1956 Jun;35(6):671-82 PMID: 13319506
Biosynthesis of fatty acids in cell-free preparations. IV. Synthesis of fatty acids from acetate by a partially purified enzyme system from rabbit mammary gland.
Biochem J. 1957 Feb;65(2):348-63 PMID: 13403915
Insulin and hepatic utilization of glucose for lipogenesis.
J Biol Chem. 1950 Oct;186(2):535-42 PMID: 14794648
The biosynthesis of fatty acids in rat liver.
J Biol Chem. 1957 Jun;226(2):615-29 PMID: 13438847
Biosynthesis of cholesterol and beta-hydroxy-beta-methylglutaric acid by extracts of liver.
J Biol Chem. 1954 May;208(1):307-13 PMID: 13174539
The effects of citrate and coenzyme A on fatty acid metabolism.
J Biol Chem. 1956 Oct;222(2):795-802 PMID: 13367047
Fasting and hepatic lipogenesis from C14-acetate.
J Biol Chem. 1952 May;196(1):25-32 PMID: 12980939
Oxidation and synthesis of fatty acids in soluble enzyme systems of animal tissues.
Clin Chem. 1955 Feb;1(1):53-67 PMID: 14364827
The occurrence and mechanism of the hexose monophosphate shunt in rat liver slices.
J Biol Chem. 1955 Jun;214(2):853-68 PMID: 14381422
Cholesterol synthesis from acetate in the diabetic liver.
J Biol Chem. 1952 Oct;198(2):895-9 PMID: 12999807
Biosynthesis of labeled fatty acids and cholesterol in experimental diabetes.
J Biol Chem. 1950 Dec;187(2):589-96 PMID: 14803440
Metabolic defects in the liver of fasted rats as shown by utilization of C14-labeled glucose and fructose.
J Biol Chem. 1953 Feb;200(2):851-7 PMID: 13034847
Terpenoid intermediates in the biosynthesis of cholesterol.
J Biol Chem. 1956 Jul;221(1):181-9 PMID: 13345809

Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103708

Published

1958-08-00

Pages

1185-95

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC1062785

Subset

External Links

PubMed source DOI: 10.1172/JCI103708 PMC Full Text View journal details

Analysis Services

Studies on the relationship between glucose oxidation and intermediary metabolism. I. The influence of glycolysis on the synthesis of cholesterol and fatty acid in normal liver.

Contact

WeChat Official Account