The clearance of heterologous protein from the circulation of normal and immunized man.

The Journal of clinical investigation ·Vol. 37 ·No. 9 ·1958-09-00 ·Pages 1306-15

FLETCHER AP, ALKJAERSIG N, SHERRY S

Abstract

暂无摘要

Keywords

PROTEINS/metabolism STREPTODORNASE AND STREPTOKINASE/in blood

MeSH Terms

Deoxyribonuclease I Humans Immunization Kinetics Male Proteins/metabolism Streptodornase and Streptokinase/blood Streptokinase Vaccination

Chemicals

Proteins Streptodornase and Streptokinase Deoxyribonuclease I Streptokinase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

FLETCHER A P

ALKJAERSIG N

SHERRY S

References (19)

19 references, click to expand

The in vivo stability of the I131 protein label of rabbit antibody in guinea pigs as determined by the quantitative precipitin reaction.
J Immunol. 1951 Nov;67(5):393-402 PMID: 14898075
The use of radioactive isotopes in immunological investigations. X. The fate of some intravenously injected native proteins in normal and immune rabbits.
Biochem J. 1957 Mar;65(3):560-9 PMID: 13412663
Antigen elimination from the blood as an early manifestation of the immune response.
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Distribution and elimination of 131 I- and 14C-labelled plasma proteins in the rabbit.
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Methods employed for purification of streptokinase.
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The turnover rate of serum albumin in man as measured by I131-tagged albumin.
J Clin Invest. 1951 Nov;30(11):1228-37 PMID: 14888700
Labelling of plasma proteins with radioactive iodine.
Biochem J. 1956 Jan;62(1):135-43 PMID: 13293164
Effects in patients of intravenous infusions of purified streptokinase preparations.
Proc Soc Exp Biol Med. 1957 Feb;94(2):254-8 PMID: 13408227
An approach to intravascular fibrinolysis in man.
Trans Assoc Am Physicians. 1957;70:288-95; discussion 295-6 PMID: 13496137
Comparative studies on the turnover of serum albumin in normal human subjects.
J Clin Invest. 1956 Oct;35(10):1161-72 PMID: 13367212
The intravascular use of streptokinase.
Ann N Y Acad Sci. 1957 Aug 30;68(1):201-6; discussion 206-8 PMID: 13479033
Tracer experiments with I131 labeled human serum albumin: distribution and degradation studies.
J Clin Invest. 1953 Aug;32(8):746-68 PMID: 13069623
I131 as an antigen label in the circulating serum of non-immune rabbits.
J Immunol. 1950 Nov;65(5):523-8 PMID: 14794917
The use of radioactive isotopes in immunological investigations. XI. The fate of some chemically modified protein antigens in normal and immune rabbits.
Biochem J. 1957 Mar;65(3):570-4 PMID: 13412664
The immunologic reactivity of bovine serum albumin labeled with trace-amounts of radioactive iodine (I131).
J Immunol. 1949 Sep;63(1):71-80 PMID: 18148078
Chemical, clinical and immunological studies on the products of human plasma fractionation XL. Quantitative separation and determination of the protein components in small amounts of normal human plasma.
J Clin Invest. 1951 Jan;30(1):99-111 PMID: 14803564
Labelled antigens and antibodies.
Annu Rev Microbiol. 1954;8:333-52 PMID: 13198111
The fate in rats of internally and externally labelled heterologous proteins.
J Immunol. 1955 Oct;75(4):315-20 PMID: 13263597
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Article Info

Journal

The Journal of clinical investigation

Abbr.

J Clin Invest

ISSN

0021-9738

DOI

10.1172/JCI103719

Published

1958-09-00

Pages

1306-15

Language

English

Region

United States

NLM ID

7802877

PMCID

PMC1062800

Subset

External Links

PubMed source DOI: 10.1172/JCI103719 PMC Full Text View journal details

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The clearance of heterologous protein from the circulation of normal and immunized man.

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