Caprine immunization against brucellosis; a summary of experiments on the isolation, properties and behaviour of a vaccine strain.

The ability of a streptomycin-non-dependent strain of Brucella melitensis to immunize goats against brucella infection and to protect against the abortion phenomenon was determined in a series of studies using both heat-killed and living cells of the strain. The data presented contrast the efficacy of both types of vaccine and demonstrate the importance of the relationship between mating date and date of vaccination in the prevention of abortion. Also included is an account of experiments on cross-immunity between infections induced by tubercle bacilli and brucellae, using monocytes from vaccinated and unvaccinated rabbits.