Genetic variation in pathogenic bacteria.

Trends in genetics : TIG ·Vol. 8 ·No. 12 ·1992-12-00 ·Pages 422-7

Robertson BD, Meyer TF

Abstract

In contrast to textbook ideas of pure cultures and defined strains, genetic variation is a fact of life in the microbial world. It not only allows pathogens to establish themselves in their chosen host, but also allows them to resist that host's subsequent attempts to evict them. Here we review some of the mechanisms that bring about this variation, and some of the functional consequences that result from it.

Related Genes

bvgS crylA emm fim fimA h2 hifB lic lifA msp1 opamp opc papA pilC pilE pilS tfp vlp yopA

MeSH Terms

Adaptation, Biological Antigens, Bacterial/genetics Bacteria/genetics,pathogenicity Bacterial Adhesion/genetics Bacterial Outer Membrane Proteins/genetics Bacterial Proteins/genetics Fimbriae, Bacterial Gene Conversion Gene Expression Regulation, Bacterial Genes, Bacterial Genetic Variation/genetics Lipopolysaccharides Recombination, Genetic Repetitive Sequences, Nucleic Acid Virulence

Chemicals

Antigens, Bacterial Bacterial Outer Membrane Proteins Bacterial Proteins Lipopolysaccharides

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Robertson B D

Max-Planck-Institut für Biologie, Abt. Infektionsbiologie, Tübingen, FRG.

Meyer T F

Article Info

Journal

Trends in genetics : TIG

Abbr.

Trends Genet

ISSN

0168-9525

DOI

10.1016/0168-9525(92)90325-x

Published

1992-12-00

Pages

422-7

Language

English

Region

England

NLM ID

8507085

Subset

External Links

PubMed source DOI: 10.1016/0168-9525(92)90325-x View journal details

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