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PMID: 13634984 Published · ppublish English Journal Article

Continuous protein synthesis in nuclei, shown by radioautography with H3-labeled amino acids.

Science (New York, N.Y.) ·Vol. 129 ·No. 3346 ·1959-02-13 ·Pages 391-2

CARNEIRO J, LEBLOND CP

Abstract

Radioautographic investigation of the cell nuclei of adult mice after injection of leucine-H(3), methionine-H(3), or glycine-H(3) shows a high uptake of tritium by chromatin material but not by nucleoli. It is concluded that protein synthesis occurs continuously within nuclear chromatin.

Keywords
AMINO ACIDS/metabolism CELL NUCLEUS/metabolism PROTEINS/metabolism
MeSH Terms
Amino Acids/metabolism Animals Autoradiography Cell Nucleolus Cell Nucleus/metabolism Glycine Leucine Methionine Mice Protein Biosynthesis Proteins/metabolism Tritium
Chemicals
Amino Acids Proteins Tritium Methionine Leucine Glycine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
CARNEIRO J
LEBLOND C P
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.129.3346.391
Published
1959-02-13
Pages
391-2
Language
English
Region
United States
NLM ID
0404511
Subset
OM
External Links
PubMed source DOI: 10.1126/science.129.3346.391 View journal details
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