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PMID: 1365396 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Master genes in mammalian repetitive DNA amplification.

Trends in genetics : TIG ·Vol. 8 ·No. 9 ·1992-09-00 ·Pages 307-11

Deininger PL, Batzer MA, Hutchison CA, Edgell MH

Abstract

The analysis of species-specific subfamilies of both the LINE and SINE mammalian repetitive DNA families suggests that such subfamilies have arisen by amplification of an extremely small group of 'master' genes. In contrast to the master genes, the vast majority of both SINEs and LINEs appear to behave like psudogenes in their inability to undergo extensive amplification.

MeSH Terms
Animals DNA/genetics Gene Amplification/genetics Mammals Models, Genetic Multigene Family Repetitive Sequences, Nucleic Acid Transcription, Genetic
Chemicals
DNA
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Deininger P L
Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center, New Orleans 70112.
Batzer M A
Hutchison C A
Edgell M H
Article Info
Journal
Trends in genetics : TIG
Abbr.
Trends Genet
ISSN
0168-9525
Published
1992-09-00
Pages
307-11
Language
English
Region
England
NLM ID
8507085
Subset
IM
Grants
NIAID NIH HHS · AI08998 · United States
NIGMS NIH HHS · GM21313 · United States
NHGRI NIH HHS · R01 HG00340 · United States
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