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PMID: 1369415 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Transcriptional regulation by the nuclear receptor superfamily.

Current opinion in biotechnology ·Vol. 3 ·No. 6 ·1992-12-00 ·Pages 597-602

Yu VC, Näär AM, Rosenfeld MG

Abstract

In the past year, additional experimental data have expanded our understanding of the molecular mechanisms that underlie nuclear receptor control of regulatory programs. It is increasingly clear that steroid members (e.g. glucocorticoid and estrogen) and non-steroid members (e.g. retinoic acid, thyroid hormone, and vitamin D) of the nuclear receptor superfamily may utilize distinct strategies in achieving their complex control of gene regulation.

MeSH Terms

Animals Carrier Proteins/genetics,metabolism Cell Nucleus/metabolism Chromosomes, Human, Pair 15 Chromosomes, Human, Pair 17 Gene Expression Regulation Humans Leukemia, Promyelocytic, Acute Multigene Family Receptors, Cell Surface/genetics,metabolism Receptors, Retinoic Acid Retinoid X Receptors Retinoids/metabolism Transcription Factors Transcription, Genetic Translocation, Genetic Tretinoin/metabolism

Chemicals

Carrier Proteins Receptors, Cell Surface Receptors, Retinoic Acid Retinoid X Receptors Retinoids Transcription Factors Tretinoin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Yu V C

Howard Hughes Medical Institute, School of Medicine, University of California, San Diego, La Jolla 92093-0648.

Näär A M

Rosenfeld M G

Article Info

Journal

Current opinion in biotechnology

Abbr.

Curr Opin Biotechnol

ISSN

0958-1669

DOI

10.1016/0958-1669(92)90002-z

Published

1992-12-00

Pages

597-602

Language

English

Region

England

NLM ID

9100492

External Links

PubMed source DOI: 10.1016/0958-1669(92)90002-z View journal details

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