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PMID: 13720237 Published · ppublish English Journal Article

Suppressor of pyrimidine 3 mutants of Neurospora and its relation to arginine synthesis.

Science (New York, N.Y.) ·Vol. 134 ·No. 3477 ·1961-08-18 ·Pages 470-1

DAVIS RH

Abstract

The basis of the mutant phenotype of the pyr 3a strain of Neurospora appears to be the arginine sensitivity of an early step in pyrimidine synthesis. The effect of a suppressor mutation which renders pyr 3a pyrimidine-independent is to reduce arginine levels in the mycelium by its effect on ornithine transcarbamylase.

Keywords
ARGININE/metabolism PYRIMIDINES/metabolism
MeSH Terms
Arginine/metabolism Biochemical Phenomena Mutation Neurospora Pyrimidines/metabolism Suppression, Genetic
Chemicals
Pyrimidines Arginine pyrimidine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
DAVIS R H
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.134.3477.470
Published
1961-08-18
Pages
470-1
Language
English
Region
United States
NLM ID
0404511
Subset
OM
External Links
PubMed source DOI: 10.1126/science.134.3477.470 View journal details
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