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PMID: 13771292 Published · ppublish English Journal Article

Increased dihydrofolate reductase activity as a possible basis of drug resistance in leukaemia.

Nature ·Vol. 189 ·1961-01-07 ·Pages 39-42

MISRA DK, HUMPHREYS SR, FRIEDKIN M, GOLDIN A, CRAWFORD EJ

Abstract

暂无摘要

Keywords
DEHYDROGENASES/metabolism FOLIC ACID ANTAGONISTS/pharmacology LEUKEMIA/metabolism
MeSH Terms
Biochemical Phenomena Drug Resistance Folic Acid Antagonists/pharmacology Humans Leukemia/metabolism Oxidation-Reduction Oxidoreductases/metabolism Tetrahydrofolate Dehydrogenase
Chemicals
Folic Acid Antagonists Oxidoreductases Tetrahydrofolate Dehydrogenase
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
MISRA D K
HUMPHREYS S R
FRIEDKIN M
GOLDIN A
CRAWFORD E J
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/189039a0
Published
1961-01-07
Pages
39-42
Language
English
Region
England
NLM ID
0410462
Subset
OM
External Links
PubMed source DOI: 10.1038/189039a0 View journal details
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