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PMID: 13789820 Published · ppublish English Journal Article

In vitro studies on the interaction between mouse peritoneal macrophages and strains of Salmonella and Escherichia coli.

The Journal of experimental medicine ·Vol. 112 ·1960-08-01 ·Pages 403-17

JENKIN C, BENACERRAF B

Abstract

Virulent strains of Salmonella opsonized with normal mouse plasma are never phagocytosed as well as avirulent strains. The virulent strains of Salmonella phagocytosed after opsonization with normal mouse plasma are able to multiply within normal mouse peritoneal macrophages, whereas under similar experimental conditions the avirulent strains are killed. When virulent strains of Salmonella are opsonized with specific antiserum or plasma from BCG-infected mice, they are treated by normal mouse macrophages as if they were avirulent. Virulent bacteria opsonized with BCG plasma are phagocytosed and killed better by peritoneal macrophages from BCG-infected mice, than peritoneal macrophages from normal mice.

Keywords
ESCHERICHIA COLI MACROPHAGES PERITONEOSCOPY SALMONELLA
MeSH Terms
Animals Escherichia coli In Vitro Techniques Laparoscopy Macrophages Macrophages, Peritoneal Mice Phagocytosis Salmonella Salmonella typhimurium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
JENKIN C
BENACERRAF B
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19 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.112.2.403
Published
1960-08-01
Pages
403-17
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2137224
Subset
OM
External Links
PubMed source DOI: 10.1084/jem.112.2.403 PMC Full Text View journal details
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