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PMID: 1379552 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Molecular cloning and characterization of a novel calcium channel from rabbit brain.

FEBS letters ·Vol. 308 ·No. 1 ·1992-08-10 ·Pages 7-13

Niidome T, Kim MS, Friedrich T, Mori Y

Abstract

The complete amino acid sequence of a novel calcium channel (designated BII) from rabbit brain has been deduced by cloning and sequencing the cDNA. The BII calcium channel is structurally more closely related to the BI calcium channel than to the cardiac and skeletal muscle L-type calcium channels. Blot hybridization analysis of RNA from different tissues and from different regions of the brain shows that the BII calcium channel is distributed predominantly in the brain, being abundant in the cerebral cortex, hippocampus and corpus striatum.

MeSH Terms

Amino Acid Sequence Animals Autoradiography Base Sequence Brain/metabolism Calcium Channels/genetics,metabolism Cloning, Molecular DNA Molecular Sequence Data RNA/metabolism Rabbits Sequence Alignment

Chemicals

Calcium Channels RNA DNA

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Niidome T

Department of Medical Chemistry, Kyoto University Faculty of Medicine, Japan.

Kim M S

Friedrich T

Mori Y

Article Info

Journal

FEBS letters

Abbr.

FEBS Lett

ISSN

0014-5793

DOI

10.1016/0014-5793(92)81038-n

Published

1992-08-10

Pages

7-13

Language

English

Region

England

NLM ID

0155157

Subset

Databases

GENBANK

S39995, S39996, S40001, S40008, S40009, S40010, X66431, X66432, X67855, X67856

External Links

PubMed source DOI: 10.1016/0014-5793(92)81038-n View journal details

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Molecular cloning and characterization of a novel calcium channel from rabbit brain.

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