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PMID: 13798502 Published · ppublish English Journal Article

Rapid induction of allergic encephalomyelitis in rats without the use of mycobacteria.

Science (New York, N.Y.) ·Vol. 131 ·No. 3411 ·1960-05-13 ·Pages 1448

BELL J, PATERSON PY

Abstract

Rats, in contrast to certain other species of animals reported, have a striking capacity to develop allergic encephalomyelitis within 2 to 3 weeks following one injection of spinal cord antigen combined with Freund's incomplete adjuvant-that is, adjuvant prepared without addition of killed mycobacteria.

Keywords
ALLERGY/experimental ENCEPHALOMYELITIS/experimental
MeSH Terms
Adjuvants, Immunologic Animals Antigens Encephalomyelitis Encephalomyelitis, Autoimmune, Experimental Freund's Adjuvant Hypersensitivity Lipids Rats Spinal Cord
Chemicals
Adjuvants, Immunologic Antigens Lipids incomplete Freund's adjuvant Freund's Adjuvant
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
BELL J
PATERSON P Y
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.131.3411.1448
Published
1960-05-13
Pages
1448
Language
English
Region
United States
NLM ID
0404511
Subset
OM
External Links
PubMed source DOI: 10.1126/science.131.3411.1448 View journal details
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