Genetic control of two gamma-globulin isoantigenic sites in domestic rabbits.

Results of immunochemical analysis of sera from 335 offspring of 81 litters of rabbits are consistent with the hypothesis that the isoantigenic sites, RGG-I and RGG-II, of the gamma-globulins are controlled by a single allelic pair of autosomal genes with both specificities exhibited by the heterozygote. The three genotypes may be designated gamma(I)/gamma(I), gamma(II)/gamma(II), and gamma(I)/gamma(II).