Comparison of the intracellular activities of clarithromycin and erythromycin against Mycobacterium avium complex strains in J774 cells and in alveolar macrophages from human immunodeficiency virus type 1-infected individuals.
The intracellular activities of clarithromycin and erythromycin, alone and in combination with other antimicrobial agents, were tested against Mycobacterium avium complex (MAC) strains inside mouse J774 cells and inside alveolar macrophages obtained from human immunodeficiency type 1-infected individuals. Clarithromycin alone had greater intracellular activity than erythromycin alone, and drug combinations that included clarithromycin were usually more active than combinations that included erythromycin.
14 references, click to expand
-
Killing by antimycobacterial agents of AIDS-derived strains of Mycobacterium avium complex inside cells of the mouse macrophage cell line J774.Am Rev Respir Dis. 1989 Nov;140(5):1198-203 PMID: 2817581
-
In-vitro activity of erythromycin against atypical mycobacteria.J Infect Dis. 1971 Feb;123(2):216-9 PMID: 5544146
-
Activities of sparfloxacin, azithromycin, temafloxacin, and rifapentine compared with that of clarithromycin against multiplication of Mycobacterium avium complex within human macrophages.Antimicrob Agents Chemother. 1991 Jul;35(7):1356-9 PMID: 1656860
-
Effects of antimicrobial agents on survival of Mycobacterium avium complex inside alveolar macrophages obtained from patients with human immunodeficiency virus infection.Antimicrob Agents Chemother. 1991 Aug;35(8):1621-5 PMID: 1929335
-
In vitro and in vivo activities of clarithromycin against Mycobacterium avium.Antimicrob Agents Chemother. 1989 Sep;33(9):1531-4 PMID: 2530933
-
[Bacteriostatic and bactericidal study of rifabutine and clofazimine in combination against Mycobacterium avium-intracellulare and Mycobacterium xenopi].Pathol Biol (Paris). 1989 Jun;37(5 Pt 2):585-90 PMID: 2552379
-
Activities of clarithromycin, sulfisoxazole, and rifabutin against Mycobacterium avium complex multiplication within human macrophages.Antimicrob Agents Chemother. 1990 Aug;34(8):1508-11 PMID: 2171421
-
Antimicrobial drugs, microorganisms, and phagocytes.Rev Infect Dis. 1989 Mar-Apr;11(2):213-45 PMID: 2649959
-
In vitro activities of several new macrolide antibiotics against Mycobacterium avium complex.Antimicrob Agents Chemother. 1989 Sep;33(9):1614-6 PMID: 2817858
-
Broth microdilution testing of susceptibilities to 30 antimicrobial agents of Mycobacterium avium strains from patients with acquired immune deficiency syndrome.Antimicrob Agents Chemother. 1987 Oct;31(10):1579-84 PMID: 3501698
-
Uptake of antibiotics by human alveolar macrophages.Am Rev Respir Dis. 1984 Jun;129(6):933-7 PMID: 6732052
-
A method for testing for synergy with any number of agents.J Infect Dis. 1978 Feb;137(2):122-30 PMID: 627734
-
Extracellular and intracellular activities of clarithromycin used alone and in association with ethambutol and rifampin against Mycobacterium avium complex.Antimicrob Agents Chemother. 1991 Mar;35(3):462-70 PMID: 1828135
-
[In vitro sensitivity of Mycobacterium avium and Mycobacterium xenopi to erythromycin, roxithromycin and doxycycline].Pathol Biol (Paris). 1989 Jun;37(5 Pt 2):565-7 PMID: 2797881
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