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PMID: 13935529 Published · ppublish English Journal Article

Thyroxine: effects on amino acid incorporation into protein in vivo.

Science (New York, N.Y.) ·Vol. 140 ·No. 3574 ·1963-06-28 ·Pages 1417-8

MICHELS R, CASON J, SOKOLOFF L

Abstract

Treatment of rats with L-thyroxine increases the incorporation in vivo of radioactive amino acids into protein of liver, kidney, and heart, but not of spleen, testis, or brain. The distribution of the effect among the organs is the same as that observed in thyroxine stimulation of oxidative metabolism. Thus, stimulation of protein synthesis seems to be a physiological action of the thyroid hormone.

Keywords
PROTEIN METABOLISM THYROXIN
MeSH Terms
Amino Acids Animals Liver Male Protein Biosynthesis Proteins/metabolism Rats Thyroid Hormones Thyroxine
Chemicals
Amino Acids Proteins Thyroid Hormones Thyroxine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
MICHELS R
CASON J
SOKOLOFF L
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1963-06-28
Pages
1417-8
Language
English
Region
United States
NLM ID
0404511
Subset
OM
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