The steady state transmembrane resting potential difference (V(m)) has been measured in quiescent papillary muscles. V(m) was determined as a function of the external K concentration in Cl and SO(4) solutions and compared with the K equilibrium potential. Other measurements were made after replacement of external Na by choline, K by Rb and Cs, and Cl by SO(4), CH(3)SO(4), and NO(3). Effects on V(m) of albumin, temperature, and variation in internal K concentration are described.
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