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PMID: 13959284 Published · ppublish English Journal Article

Calculation of the albumin catabolic rate in the non-steady state.

The Journal of general physiology ·Vol. 46 ·1963-01-00 ·Pages 405-13

FRANKS JJ

Abstract

Methods which are in current use for the calculation of the albumin breakdown rate apply only to the steady state animal. In this paper a simple but more general method based on analyses of I(131)-albumin tracer data is presented. It utilizes easily measured plasma specific activity and excretory data and is equally applicable to the steady and non-steady states.

Keywords
PROTEIN METABOLISM SERUM ALBUMIN
MeSH Terms
Albumins Animals Proteins/metabolism Serum Albumin
Chemicals
Albumins Proteins Serum Albumin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
FRANKS J J
References (8)
8 references, click to expand
  1. The nature and rates of excretion of radioactive breakdown products of I131-albumin in the rabbit.
    J Gen Physiol. 1959 Nov;43:397-413 PMID: 13847673
  2. The kinetics of the distribution and breakdown of 1131-albumin in the rabbit. Observations on several mathematical descriptions.
    J Gen Physiol. 1959 Nov;43:415-44 PMID: 14436924
  3. A practical method for plasma albumin turnover studies.
    Strahlentherapie. 1958;107(Sonderbd. 38):290-7 PMID: 13603158
  4. The turnover rate of serum albumin in man as measured by I131-tagged albumin.
    J Clin Invest. 1951 Nov;30(11):1228-37 PMID: 14888700
  5. Labelling of plasma proteins with radioactive iodine.
    Biochem J. 1956 Jan;62(1):135-43 PMID: 13293164
  6. The role of the gut in albumin catabolism. II. Studies in enterectomized rabbits.
    J Gen Physiol. 1963 Jan;46:427-34 PMID: 13959286
  7. The behavior of I 131-labeled plasma proteins in vivo.
    Ann N Y Acad Sci. 1957 Aug 30;70(1):19-25 PMID: 13488251
  8. The role of the gut in albumin catabolism. I. Studies in the jejunoileectomized rabbit.
    J Gen Physiol. 1963 Jan;46:415-25 PMID: 13959285
Article Info
Journal
The Journal of general physiology
Abbr.
J Gen Physiol
ISSN
0022-1295
DOI
10.1085/jgp.46.3.405
Published
1963-01-00
Pages
405-13
Language
English
Region
United States
NLM ID
2985110R
PMCID
PMC2195279
Subset
OM
External Links
PubMed source DOI: 10.1085/jgp.46.3.405 PMC Full Text View journal details
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