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PMID: 1397271 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation.

FEBS letters ·Vol. 310 ·No. 2 ·1992-09-28 ·Pages 193-6

Orellana M, Fuentes O, Rosenbluth H, Lara M, Valdés E

Abstract

In this work the microsomal lauric acid omega-hydroxylation, fatty acid peroxisomal beta-oxidation, and the levels of cytochrome P-450 IVA1 were studied in liver tissue from starved rats. Starvation increased the peroxisomal beta-oxidation and the microsomal hydroxylation of fatty acids. The correlation between these activities would support the proposal that both processes are linked, contributing in part to catabolism of fatty acids in liver of starved rats.

MeSH Terms

Animals Blotting, Western Catalase/metabolism Cytochrome P-450 Enzyme System/metabolism Electrophoresis, Polyacrylamide Gel Fatty Acids/metabolism Hydroxylation Liver/enzymology,metabolism Male Microbodies/enzymology,metabolism Microsomes, Liver/enzymology,metabolism Oxidation-Reduction Rats Rats, Wistar Starvation/metabolism

Chemicals

Fatty Acids Cytochrome P-450 Enzyme System Catalase

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Orellana M

Departamento de Bioquímica, Facultad de Medicina, Universidad de Chile, Santiago.

Fuentes O

Rosenbluth H

Lara M

Valdés E

Article Info

Journal

FEBS letters

Abbr.

FEBS Lett

ISSN

0014-5793

DOI

10.1016/0014-5793(92)81327-i

Published

1992-09-28

Pages

193-6

Language

English

Region

England

NLM ID

0155157

Subset

External Links

PubMed source DOI: 10.1016/0014-5793(92)81327-i View journal details

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Modulation of rat liver peroxisomal and microsomal fatty acid oxidation by starvation.

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