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PMID: 14057354 Published · ppublish English Journal Article

RUBELLA VIRUS: NEUTRALIZING ANTIBODY IN COMMERCIAL GAMMA GLOBULIN.

Science (New York, N.Y.) ·Vol. 142 ·No. 3588 ·1963-10-04 ·Pages 58-60

SCHIFF GM, SEVER JL, HUEBNER RJ

Abstract

In 19 lots of standard commercial gamma globulin from humans, the titers of antibody neutralizing rubella virus varied from, 256 to 2048. The titers could not be correlated with geographic location of the donors, method of extraction, or tissue source. Samples of gamma globulin from rubella convalescents had titers of 4096. These titers were approximately 20 times higher than those in serum specimens from patients ill with natural or experimental infection. Serum antibody appears to persist for a number of years at nearly the original titers.

Keywords
ANTIBODIES GAMMA GLOBULIN RUBELLA VERTEBRATE VIRUSES
MeSH Terms
Animals Antibodies Antibodies, Blocking Antibodies, Neutralizing Humans Rubella Rubella virus Vertebrates Viruses gamma-Globulins
Chemicals
Antibodies Antibodies, Blocking Antibodies, Neutralizing gamma-Globulins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
SCHIFF G M
SEVER J L
HUEBNER R J
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1963-10-04
Pages
58-60
Language
English
Region
United States
NLM ID
0404511
Subset
OM
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