CIRCULARITY OF THE REPLICATING FORM OF A SINGLE-STRANDED DNA VIRUS.

Science (New York, N.Y.) ·Vol. 143 ·No. 3601 ·1964-01-03 ·Pages 47-9

CHANDLER B, HAYASHI M, HAYASHI MN, SPIEGELMAN S

Abstract

Electron micrographs of purified replicating form DNA of the bacteriophage øX-174 show that it has ring structure. The circular property may explain both the abnormally high sedimentation coefficient and the great resistance of this DNA to irreversible heat denaturation. Intactness of the circle is required for the control of strand selection during transcription into complementary copies of RNA.

Keywords

CHEMISTRY COLIPHAGES DNA VIRAL EXPERIMENTAL LAB STUDY MICROSCOPY ELECTRON

MeSH Terms

Chemical Phenomena Chemistry Coliphages DNA Replication DNA Viruses DNA, Single-Stranded DNA, Viral Electrons Microscopy Microscopy, Electron Research

Chemicals

DNA, Single-Stranded DNA, Viral

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

CHANDLER B

HAYASHI M

HAYASHI M N

SPIEGELMAN S

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.143.3601.47

Published

1964-01-03

Pages

47-9

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.143.3601.47 View journal details

Analysis Services

CIRCULARITY OF THE REPLICATING FORM OF A SINGLE-STRANDED DNA VIRUS.

Contact

WeChat Official Account