HEMOGLOBIN SOLUBILITY AND ALPHA-CHAIN STRUCTURE IN CROSSES BETWEEN TWO INBREAD MOUSE STRAINS.

Science (New York, N.Y.) ·Vol. 143 ·No. 3603 ·1964-01-17 ·Pages 252-3

HUTTON JJ, SCHWEET RS, WOLFE HG, RUSSELL ES

Abstract

In genetic crosses between mouse strains with low and high solubilities of hemoglobin, solubility segregated as a Mendelian unit and appeared to be determined by the alleles controlling alpha-chain structure. New data eliminate close linkage between the alpha-chain locus and genetic markers in linkage groups Ill, IV, XI, XIII, and XVI. Simplified methods are presented for screening differences inalpha-chain peptides and solubility.

Keywords

CHEMISTRY EXPERIMENTAL LAB STUDY GENETICS HEMOGLOBIN MICE

MeSH Terms

Alleles Animals Chemical Phenomena Chemistry Genetic Linkage Genetic Markers Genetics Hemoglobins Mice Peptides Research Solubility

Chemicals

Genetic Markers Hemoglobins Peptides

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

HUTTON J J

SCHWEET R S

WOLFE H G

RUSSELL E S

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.143.3603.252

Published

1964-01-17

Pages

252-3

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.143.3603.252 View journal details

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