ACTIVE 'JUVENILE' CIRRHOSIS CONSIDERED AS PART OF A SYSTEMIC DISEASE AND THE EFFECT OF CORTICOSTEROID THERAPY.

Gut ·Vol. 4 ·1963-12-00 ·Pages 378-93

READ AE, SHERLOCK S, HARRISON CV

Abstract

This is a clinical study of 81 patients (32 male and 49 female), who are not alcoholics, with jaundice of hepato-cellular type lasting longer than three months. Forty-nine of these patients were under 21 years of age. The natural history of the condition and the response to corticosteroid therapy is described; good symptomatic relief can be achieved with corticosteroids but they do not seem to prolong life. The aetiology is discussed with special reference to the relationship to viral hepatitis, to systemic lupus erythematosus, and to other disturbances of immunity.

Keywords

ADOLESCENCE ADRENAL CORTEX HORMONES HEPATITIS INFECTIOUS JAUNDICE CHRONIC IDIOPATHIC LIVER CIRRHOSIS LUPUS ERYTHEMATOSUS SYSTEMIC

MeSH Terms

Adolescent Adrenal Cortex Hormones Communicable Diseases Female Glucocorticoids Hepatitis Hepatitis A Humans Jaundice Jaundice, Chronic Idiopathic Liver Cirrhosis Lupus Erythematosus, Systemic Male

Chemicals

Adrenal Cortex Hormones Glucocorticoids

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

READ A E

SHERLOCK S

HARRISON C V

References (33)

33 references, click to expand

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Article Info

Journal

Gut

Abbr.

Gut

ISSN

0017-5749

DOI

10.1136/gut.4.4.378

Published

1963-12-00

Pages

378-93

Language

English

Region

England

NLM ID

2985108R

PMCID

PMC1413482

Subset

External Links

PubMed source DOI: 10.1136/gut.4.4.378 PMC Full Text View journal details

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ACTIVE 'JUVENILE' CIRRHOSIS CONSIDERED AS PART OF A SYSTEMIC DISEASE AND THE EFFECT OF CORTICOSTEROID THERAPY.

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