Effects of post-learning smoking on memory consolidation.

The effects of immediate post-learning smoking of low and medium nicotine delivery cigarettes were compared to those of smoking a denicotinised cigarette and a no-smoking control condition in a paired-associate learning task. Thirty-nine male smokers were tested for retention of the memorised material at 1 week post-learning. All subjects received all conditions in a repeated measures design. The low nicotine condition was associated with significantly fewer errors on first trial of recall and fewer total errors to criterion. There were no differences in performance reported between the no-smoking and zero nicotine conditions. The medium nicotine condition produced results part way between the no-smoking and low nicotine conditions. Results are discussed in terms of the effects of nicotine on long-term consolidation mechanisms.