EFFECT OF BROMINATION ON THE BIOLOGICAL ACTIVITIES OF TRANSFER RNA OF ESCHERICHIA COLI.

Science (New York, N.Y.) ·Vol. 144 ·No. 3620 ·1964-05-15 ·Pages 856-9

YU CT, ZAMECNIK PC

Abstract

A transfer RNA molecule accepts a particular amino acid from an activating enzyme and subsequently transfers it to the end of a growing peptide chain, in association with ribosomes and messenger RNA. The acceptor and transfer functions of transfer RNA differ in their sensitivity to damage by bromination, and thus appear to comprise different areas on the transfer RNA molecule.

Keywords

ADENINE NUCLEOTIDES BROMINE CARBON ISOTOPES ESCHERICHIA COLI EXPERIMENTAL LAB STUDY GENETIC CODE GUANINE NUCLEOTIDES LYSINE NUCLEOSIDES NUCLEOTIDES PHARMACOLOGY PHENYLALANINE PROTEIN METABOLISM PYRIMIDINES RIBOSOMES RNA BACTERIAL RNA MESSENGER URACIL NUCLEOTIDES VALINE

MeSH Terms

Adenine Nucleotides Amino Acids Bromine Carbon Isotopes Escherichia coli Genetic Code Guanine Nucleotides Halogenation Lysine Nucleosides Nucleotides Peptides Pharmacology Phenylalanine Proteins/metabolism Pyrimidines RNA RNA, Bacterial RNA, Messenger RNA, Transfer Research Ribosomes Uracil Nucleotides Valine

Chemicals

Adenine Nucleotides Amino Acids Carbon Isotopes Guanine Nucleotides Nucleosides Nucleotides Peptides Proteins Pyrimidines RNA, Bacterial RNA, Messenger Uracil Nucleotides Phenylalanine RNA RNA, Transfer Valine Lysine Bromine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

YU C T

ZAMECNIK P C

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.144.3620.856

Published

1964-05-15

Pages

856-9

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.144.3620.856 View journal details

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EFFECT OF BROMINATION ON THE BIOLOGICAL ACTIVITIES OF TRANSFER RNA OF ESCHERICHIA COLI.

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