STAPHYLOCOCCAL ALPHA-HEMOLYSIN: DETECTION ON THE ERYTHROCYTE MEMBRANE BY IMMUNOFLUORESCENCE.

Science (New York, N.Y.) ·Vol. 145 ·No. 3633 ·1964-08-14 ·Pages 714-5

KLAINER AS, MADOFF MA, COOPER LZ, WEINSTEIN L

Abstract

Purified staphylococcal alpha-hemolysin (but not the toxoid) was demonstrated on the surface of rabbit and human erythrocytes by immunofluorescence. This occurred during the period of maximal hemolysis and was a transient event. These findings have been analyzed in relation to previous data on the kinetics of leakage of both small and complex molecular constituents of the erythrocyte.

Keywords

ERYTHROCYTES EXPERIMENTAL LAB STUDY FLUORESCENT ANTIBODY TECHNIC HEMOLYSINS HEMOLYSIS MICROSCOPY FLUORESCENCE RABBITS STAPHYLOCOCCUS TOXINS AND ANTITOXINS

MeSH Terms

Animals Antitoxins Bacterial Toxins Erythrocyte Membrane Erythrocytes Fluorescence Fluorescent Antibody Technique Hemolysin Proteins Hemolysis Humans Microscopy Microscopy, Fluorescence Rabbits Research Staphylococcus Toxins, Biological

Chemicals

Antitoxins Bacterial Toxins Hemolysin Proteins Toxins, Biological staphylococcal alpha-toxin

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

KLAINER A S

MADOFF M A

COOPER L Z

WEINSTEIN L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.145.3633.714

Published

1964-08-14

Pages

714-5

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.145.3633.714 View journal details

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STAPHYLOCOCCAL ALPHA-HEMOLYSIN: DETECTION ON THE ERYTHROCYTE MEMBRANE BY IMMUNOFLUORESCENCE.

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