INTESTINAL PHOSPHATASE ACTIVITY: ACCELERATION OF INCREASE BY PUROMYCIN AND ACTINOMYCIN.

Science (New York, N.Y.) ·Vol. 144 ·No. 3617 ·1964-04-24 ·Pages 414-6

MOOG F

Abstract

Alkaline phosphatase activity of the mouse duodenum normally increases 20-fold between 13 and 20 days. Activity at 15 days is raised two to three times above normal by administering actinomycin D, puromycin, or the aminonucleoside of puromycin at 13 or 14 days. Phosphatase activity in the jejunum and kidney are not similarly affected.

Keywords

ACTINOMYCIN ALKALINE PHOSPHATASE ANTIBIOTICS DUODENUM EXPERIMENTAL LAB STUDY JEJUNUM KIDNEY MICE NUCLEOSIDES PHARMACOLOGY PUROMYCIN

MeSH Terms

Alkaline Phosphatase Animals Anti-Bacterial Agents Dactinomycin Duodenum Jejunum Kidney Mice Nucleosides Pharmacology Puromycin Research

Chemicals

Anti-Bacterial Agents Nucleosides Dactinomycin Puromycin Alkaline Phosphatase

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

MOOG F

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.144.3617.414

Published

1964-04-24

Pages

414-6

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.144.3617.414 View journal details

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