HISTONES: SPECIES AND TISSUE SPECIFICITY.

Science (New York, N.Y.) ·Vol. 145 ·No. 3636 ·1964-09-04 ·Pages 1059-61

NEIDLE A, WAELSCH H

Abstract

Within a given species (rat, mouse, guinea pig, rabbit) the histones of brain, liver, and kidney are indistinguishable on disc electrophoresis in polyacrylamide gels. However, characteristic species differences were observed. In the immature rat, the histones of brain and liver, while very similar to each other, differ from those of the adult. The histones of the thymus of the immature and adult rat exhibited a pattern corresponding to that of the immature brain and liver.

Keywords

ANIMALS NEWBORN BRAIN ELECTROPHORESIS EXPERIMENTAL LAB STUDY GUINEA PIGS HISTONES KIDNEY LIVER MICE RABBITS RATS SPECIES SPECIFICITY

MeSH Terms

Animals Animals, Newborn Brain Electrophoresis Guinea Pigs Histones Kidney Liver Mice Organ Specificity Rabbits Rats Research Species Specificity

Chemicals

Histones

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

NEIDLE A

WAELSCH H

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.145.3636.1059

Published

1964-09-04

Pages

1059-61

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.145.3636.1059 View journal details

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