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PMID: 14172640 Published · ppublish English Journal Article

RUBELLA VIRUS: INHIBITION IN VITRO BY AMANTADINE HYDROCHLORIDE.

Science (New York, N.Y.) ·Vol. 145 ·No. 3639 ·1964-09-25 ·Pages 1443-4

MAASSAB HF, COCHRAN KW

Abstract

Amantadine (or 1-adamantanamine) hydrochloride, a compound reported to be active against influenza viruses and Sendai virus, inhibited the growth of rubella virus in tissue culture. The antiviral activity appears at an early phase of the infection and is not due to direct inactivation of the virus.

Keywords
ANTIVIRAL AGENTS EXPERIMENTAL LAB STUDY PHARMACOLOGY RUBELLA TISSUE CULTURE VERTEBRATE VIRUSES VIRUS CULTIVATION
MeSH Terms
Amantadine Animals Antiviral Agents Immunologic Tests In Vitro Techniques Orthomyxoviridae Pharmacology Research Rubella Rubella virus Tissue Culture Techniques Vertebrates Virus Cultivation Viruses
Chemicals
Antiviral Agents Amantadine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
MAASSAB H F
COCHRAN K W
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.145.3639.1443
Published
1964-09-25
Pages
1443-4
Language
English
Region
United States
NLM ID
0404511
Subset
OM
External Links
PubMed source DOI: 10.1126/science.145.3639.1443 View journal details
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