ADENOVIRUS-LIKE PARTICLES FROM CANCERS INDUCED BY ADENOVIRUS-12 BUT FREE OF INFECTIOUS VIRUS.

Science (New York, N.Y.) ·Vol. 145 ·No. 3637 ·1964-09-11 ·Pages 1190-2

SMITH KO, MELNICK JL

Abstract

Particles resembling adenovirus were recovered from tumors induced by adenovirus-12. The particles were similar to incomplete adenovirus in size, subunit morphology, and density. The presence of such incomplete viral units helps to explain why attempts to isolate infectious virus from adenovirus-induced tumors have failed despite the serological evidence that viral elements are present.

Keywords

ADENOVIRUS EXPERIMENTAL LAB STUDY HAMSTERS NEOPLASMS EXPERIMENTAL TISSUE CULTURE VIRUS CULTIVATION

MeSH Terms

Adenoviridae Adenoviridae Infections Animals Cricetinae Neoplasms Neoplasms, Experimental Research Tissue Culture Techniques Virus Cultivation

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

SMITH K O

MELNICK J L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.145.3637.1190

Published

1964-09-11

Pages

1190-2

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.145.3637.1190 View journal details

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ADENOVIRUS-LIKE PARTICLES FROM CANCERS INDUCED BY ADENOVIRUS-12 BUT FREE OF INFECTIOUS VIRUS.

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