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PMID: 1418711 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Interleukin-10.

Current opinion in immunology ·Vol. 4 ·No. 3 ·1992-06-00 ·Pages 314-20

de Waal Malefyt R, Yssel H, Roncarolo MG, Spits H, de Vries JE

Abstract

Despite the short history of interleukin-10, accumulated evidence indicates that this interleukin plays a major role in suppressing immune and inflammatory responses. Yet interleukin-10 also maintains cell viability and acts as a cofactor to promote the growth of lymphoid and myeloid cells in vitro. Here we review the present knowledge on the structure and function of interleukin-10.

MeSH Terms

Animals B-Lymphocytes/immunology Humans Interleukin-10/physiology Killer Cells, Natural/immunology Lymphocyte Activation Macrophages/immunology Mast Cells/immunology Monocytes/immunology T-Lymphocytes/immunology

Chemicals

Interleukin-10

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

de Waal Malefyt R

Human Immunology Department, DNAX Research Institute, Palo Alto, California 94304-1104.

Yssel H

Roncarolo M G

Spits H

de Vries J E

Article Info

Journal

Current opinion in immunology

Abbr.

Curr Opin Immunol

ISSN

0952-7915

DOI

10.1016/0952-7915(92)90082-p

Published

1992-06-00

Pages

314-20

Language

English

Region

England

NLM ID

8900118

Subset

External Links

PubMed source DOI: 10.1016/0952-7915(92)90082-p View journal details

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