THE SEDIMENTATION PROPERTIES OF THE SKIN-SENSITIZING ANTIBODIES OF RAGWEED-SENSITIVE PATIENTS.

The Journal of experimental medicine ·Vol. 120 ·1964-07-01 ·Pages 31-43

ANDERSEN BR, VANNIER WE

Abstract

The sedimentation coefficients of the skin-sensitizing antibodies to ragweed were evaluated by the moving partition cell method and the sucrose density gradient method. The most reliable results were obtained by sucrose density gradient ultracentrifugation which showed that the major portion of skin-sensitizing antibodies to ragweed sediment with an average value of 7.7S (7.4 to 7.9S). This is about one S unit faster than gamma-globulins (6.8S). The data from the moving partition cell method are in agreement with these results. Our studies failed to demonstrate heterogeneity of the skin-sensitizing antibodies with regard to sedimentation rate.

Keywords

ANTIBODIES HYPERSENSITIVITY IMMUNE SERUMS POLLEN ULTRACENTRIFUGATION

MeSH Terms

Ambrosia Antibodies Humans Hypersensitivity Immune Sera Pollen Ultracentrifugation gamma-Globulins

Chemicals

Antibodies Immune Sera gamma-Globulins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

ANDERSEN B R

VANNIER W E

References (15)

15 references, click to expand

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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.120.1.31

Published

1964-07-01

Pages

31-43

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2137720

Subset

External Links

PubMed source DOI: 10.1084/jem.120.1.31 PMC Full Text View journal details

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