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PMID: 14197790 Published · ppublish English Journal Article

VOLUME CONDUCTOR FIELDS OF ACTION CURRENTS.

Biophysical journal ·Vol. 4 ·1964-07-00 ·Pages 317-28

PLONSEY R

Abstract

The formulation of Lorente de Nó for the potential distribution in a volume conductor due to a contained bioelectric source is reviewed. The aforementioned formula is based on data taken from the bioelectric source in air (excised). This work is extended to the derivation of a formula which depends upon quantities available from in situ measurements. The latter formula appears to simplify to the form[FORMULA: see text]where J(n) is the normal current density flow across the surface S(o) that bounds the bioelectric source. The simplification is considered in some detail for a hypothetical action potential on a circular cylindrical axon, and is shown to be adequately substantiated for this case.

Keywords
ELECTROPHYSIOLOGY EXPERIMENTAL LAB STUDY MATHEMATICS MUSCLES NEURONS
MeSH Terms
Action Potentials Electrophysiology Mathematics Muscles Neurons Research
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
PLONSEY R
References (3)
3 references, click to expand
  1. A quantitative description of membrane current and its application to conduction and excitation in nerve.
    J Physiol. 1952 Aug;117(4):500-44 PMID: 12991237
  2. Analysis of certain errors in squid axon voltage clamp measurements.
    Biophys J. 1960 Nov;1:161-202 PMID: 13775643
  3. The electrical conductivity of living tissues as it pertains to electrocardiography. I. Review of the problem of homogeneity vs. non-homogeneity, an outline of the technical aspects of tissue resistivity measurements, and a critical and experimental analysis of certain pertinent experiments.
    Circulation. 1950 Sep;2(3):321-35 PMID: 15434933
Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
Published
1964-07-00
Pages
317-28
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1367509
Subset
OM
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