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PMID: 14261534 Published · ppublish English Journal Article

HYBRID ANTIBODY MOLECULES WITH ALLOTYPICALLY DIFFERENT L-POLYPEPTIDE CHAINS.

Science (New York, N.Y.) ·Vol. 148 ·No. 3668 ·1965-04-16 ·Pages 383-5

MANNIK M, METZGER H

Abstract

Isolated L-chains with either the A4 or the A5 allotypic markers from rabbit antibodies to 2,4-dinitrophenyl determinant recombine at random with antibody H-chains in the presence or absence of the hapten to produce hybrid precipitating antibody molecules.

Keywords
CHEMISTRY DINITROPHENOLS EXPERIMENTAL LAB STUDY GAMMA GLOBULIN IMMUNIZATION IODINE ISOTOPES PEPTIDES PRECIPITATION RABBITS RADIOMETRY
MeSH Terms
Animals Antibodies Chemical Phenomena Chemical Precipitation Chemistry Dinitrophenols Immunization Iodine Isotopes Peptides Rabbits Radiometry Research Vaccination gamma-Globulins
Chemicals
Antibodies Dinitrophenols Iodine Isotopes Peptides gamma-Globulins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
MANNIK M
METZGER H
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1965-04-16
Pages
383-5
Language
English
Region
United States
NLM ID
0404511
Subset
OM
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