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PMID: 14268729 Published · ppublish English Journal Article

FUNCTIONAL RIBOSOMAL UNIT OF GAMMA-GLOBULIN SYNTHESIS.

Science (New York, N.Y.) ·Vol. 148 ·No. 3670 ·1965-04-30 ·Pages 646-8

SCHARFF MD, UHR JW

Abstract

Nascent protein synthesis is associated with polyribosomes in extracts of lymph node cells removed from hyperimmunized rabbits, if the ribonuclease activity in such extracts is inhibited. Prior treatment of the cells with actinomycin D markedly decreases protein synthesis by polyribosomes.

Keywords
ACTINOMYCIN EXPERIMENTAL LAB STUDY GAMMA GLOBULIN IMMUNIZATION LYMPH NODES PHARMACOLOGY PROTEIN METABOLISM RABBITS RIBONUCLEASE RIBOSOMES
MeSH Terms
Animals Dactinomycin Immunization Lymph Nodes Pharmacology Proteins/metabolism Rabbits Research Ribonucleases Ribosomes Vaccination gamma-Globulins
Chemicals
Proteins gamma-Globulins Dactinomycin Ribonucleases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
SCHARFF M D
UHR J W
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
DOI
10.1126/science.148.3670.646
Published
1965-04-30
Pages
646-8
Language
English
Region
United States
NLM ID
0404511
Subset
OM
External Links
PubMed source DOI: 10.1126/science.148.3670.646 View journal details
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